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Nutrition, metabolism and Gene Therapy


Research lines

. Characterization of the genomic and functional structure of and functional pfkfb4 and pfkfb3 genes encoding 6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase.

. Study of AMPkinase role in diabetic animal models and cell preconditioning.

. Study of gluconeogenic fluxes in diabetic animal models.

. Study of cardiopulmonary bypass complications.

. Study of the influence of various ergogenic aids on physical performance.

. Assessment of the influence of acute fat provision, before exercise, on adaptation to effort and performance in long-term efforts.


Selected papers (2013)

 

 

De Bock, Katrien; Georgiadou, Maria; Schoors, Sandra; Kuchnio, Anna; Wong, Brian W.; Cantelmo, Anna Rita; Quaegebeur, Annelies; Ghesquiere, Bart; Cauwenberghs, Sandra; Eelen, Guy; Phng, Li-Kun; Betz, Inge; Tembuyser, Bieke; Brepoels, Katleen; Welti, Jonathan; Geudens, Ilse; Segura, Inmaculada; Cruys, Bert; Bifari, Franscesco; Decimo, Ilaria; Bartrons, Ramon

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting        

Cell.2013 Aug 1;154(3):651-63.

 

Lopez-Delgado, Juan C.; Esteve, Francisco; Torrado, Herminia; Rodriguez-Castro, David; Carrio, Maria L.; Farrero, Elisabet; Javierre, Casimiro; Ventura, Josep L.; Manez, Rafael

Influence of acute kidney injury on short- and long-term outcomes in patients undergoing cardiac surgery: risk factors and prognostic value of a modified RIFLE classification    

Critical Care.2013 Dec 13;17(6):R293

 

 

Novellasdemunt, Laura; Bultot, Laurent; Manzano, Anna; Ventura, Francesc; Rosa, Jose Luis; Vertommen, Didier; Rider, Mark H.; Navarr-Sabate, Aurea; Bartrons, Ramon

PFKFB3 activation in cancer cells by the p38/MK2 pathway in response to stress stimuli

Biochemical Journal.2013 Jun 15;452(3):531-43

 

 

Méndez-Lucas A, Duarte JA, Sunny NE, Satapati S, He T, Fu X, Bermúdez J,Burgess SC, Perales JC.

PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis

Journal of hepatology. 2013 Jul;59(1):105-13.

imatge personal
 

Group leader

Jose Carlos Perales
Telephone  
+34 934024295
E-mail  
jperales@idibell.cat
 
© 2017 Institut d'Investigació Biomèdica de Bellvitge



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