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Radiobiology & Cancer

Introduction

The clinical research, applied radiobiology, and experimental radiotherapy group was formed in 2010 when clinical and laboratory researchers decided to pool their research efforts. The group is comprised of enthusiastic MDs and laboratory scientists who are determined to improve patient care by integrating clinical and laboratory research. Our aim is to work together to promote and carry out research in radiation oncology.

 

One of our main areas of interest is prostate cancer therapy, particularly epidemiologic and clinical research on patient quality of life after  treatment for prostate cancer. Part of our research includes a patterns-of–care study in Europe, Latin America, Australia and New Zealand, a study that was designed to monitor changes in treatment approaches over time. We also are starting new lines of clinical and translational research based on advancements in radiation therapy delivery (Truebeam accelerator, non-invasive brachytherapy techniques for boost delivery in breast cancer, and image-guided radiotherapy).

 

The focus of the laboratory research is on identifying mechanisms of resistance to radiation and anti-EGFR (cetuximab) in order to therapeutically regain increased sensitivity to oncologic treatments.



Research lines

  • Applied Radiobiology and Experimental Radiotherapy: Radiation Resistance and EGFR Signaling Pathway, High doses in Radiation Research
  • New Therapeutic Strategies in Brachytherapy.
  • Evaluation of Quality of Life in Prostate Cancer Treatment.
  • Stereotactic Intracraneal Radiosurgery (SRS), Stereotactic Body RadioTherapy (SRBT), etc...
  • New therapeutic strategies in external radiation therapy.

                  New therapeutic strategies in external radiation therapy.

                  Clinical trials in new technologies of radiotherapy.


Selected papers 

 

Grau, C.,  Borras J.M.,  Malicki J.,  Slotman B.,  Dunscombe P., Coffey M.,  Hollywood D. Guedea F., Gasparotto C., Lievens Y.

Radiotherapy capacity in Europe.

Lancet Oncology. 2013 May;14(6):e196-8. 

 

Guedea F.,  Malicki J.

 Quality Indicators in Radiation Oncology.

International Journal of Radiation Oncology Biology Physics. 2013 Nov 1;87(3):432.

 

 

Macia M., Rubio C.,  Romero J., Hervas A.,  Vera A., Britton R., Zunino S., Sole J., de la Torre M.,  Fernandez A., Trigo L., Rodrigues R., Lurdes Salgado M., Spanish Soc Radiat Oncol SEOR, Latin American Assoc Radiation On; Portuguese Soc Radiation Oncology.

 In response to ESTRO 2012 strategy meeting: Vision for Radiation Oncology (published April 2012).

Radiotherapy and Oncology. 2013 Oct;109(1):181-2. 

Ferrer M., Guedea F.,  Francisco SuarezJ., de Paula B., Macias V., Marino A.,  Hervas A., Herruzo I., Jose Ortiz M., Ponce de Leon J., Sancho G., Boladeras A., Ayala A.,  Craven-Bratle J., Avila M., Cunillera O.,  Pardo Y., AlonsoJ., Aguilo F., Multicentric Spanish Grp Clinicall.

Quality of life impact of treatments for localized prostate cancer: Cohort study with a 5 year follow-up.

Radiotherapy and Oncology. 2013 Aug;108(2):306-13.

 

Boladeras A, Santorsa L, Gutierrez C, Martinez E, Pera J, Pino F, Suarez JF, Ferrer F, Díaz A, Polo A, Guedea F: External beam radiotherapy plus single-fraction high dose rate brachytherapy in the treatment of locally advanced prostate cancer. Radiother Oncol, pii: S0167-8140(14)00319-3, 2014

imatge personal
 

Group leader

Ferran Guedea I Edo
Adress  
Servei d\'Oncologia Radioteràpica, Institut Català d\'Oncologia. Avda Gran via de l\'Hospitalet. L\'HOSPITALET DE LLOBREGAT-08907 (SPAIN)
Telephone  
+34 932607780
E-mail  
fguedea@idibell.cat
 
© 2017 Institut d'Investigació Biomèdica de Bellvitge



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